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AELAB P100HSP Series – High Pressure Semi & Preparative HPLC Systems

The AELAB P100HSP Series high pressure semi-preparative and preparative HPLC systems provide accurate flow delivery for analytical scaling, semi-prep purification, and high-load sample processing. Using a dual-piston reciprocating pump with stable pressure regulation, the system ensures reproducible chromatographic separation in research, pharmaceutical, and industrial laboratories.
Modles : P100HSP Series
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The AELAB P100HSP Series provides analytical, semi-preparative, and high-pressure preparative pumping capabilities suitable for a wide range of chromatographic workflows. The system supports most laboratory-scale purification needs and is engineered for stable performance during long-term operation.

The redesigned pump architecture retains the classic dual-piston reciprocating parallel system while improving pressure smoothness and flow stability. The upgraded one-piece check valve structure enhances leak resistance, and the retractable piston rod simplifies routine seal replacement without disassembling the unit.

 

⚙️ Design & Construction

The AELAB P100HSP Series features a dual-piston reciprocating design equipped with a high-pressure mixing module for stable solvent delivery. The one-piece valve structure provides enhanced sealing, while the piston rod mechanism allows easy maintenance. All frames are engineered to support high-pressure loads up to 42 MPa, making the system suitable for demanding preparative chromatography.

 

🔬 Working Principle / Testing Method

The pump delivers solvent using a reciprocating dual-piston mechanism that stabilizes flow even under variable load conditions. Each model regulates its flow rate according to set parameters and continuously measures output pressure for precise chromatographic separation. The system supports analytical, semi-preparative, and preparative operational modes depending on the selected pump configuration.

 

💡 Key Advantages

  • Stable high-pressure solvent delivery up to 42 MPa for preparative workflows
  • Wide flow rate ranges from 0.001 mL/min to 120 mL/min across all models
  • Enhanced flow precision with RSD control for reproducible separation
  • Improved check-valve and sealing structure for reduced leakage risk
  • Automatic piston-seal retraction for simplified maintenance
  • Compatible with buffer salt systems and high-load purifications
  • Low pulsation delivery for consistent chromatographic baselines

 

🔗 Connectivity & Integration

The system integrates with standard chromatography workstations and supports PC-based data acquisition. External control interfaces allow connection to detectors, fraction collectors, and chromatography software platforms for GLP-compliant operation and audit-ready data tracking.

 

🧠 Model Insight

Model Specifications
P100 0.001–10 mL/min; 42 MPa; Dual-piston analytical pump
P100SP 0.01–40 mL/min; 0–25 MPa; Semi-preparative pump
P100HSP 0.01–50 mL/min; 0–42 MPa; High pressure semi-preparative system
P100HP 0.01–120 mL/min; 0–42 MPa; High pressure preparative system

 

🧪 Testing Applications

The AELAB P100HSP Series is suitable for pharmaceutical purification, biochemical separation, natural product extraction, synthetic compound isolation, environmental sample cleanup, and preparative fraction collection in both research and industrial laboratories.

 

Compliance & Quality Assurance

The system is manufactured under strict AELAB quality control, meeting CE, ISO, and GLP instrumentation guidelines. Each pump undergoes calibration and performance verification for pressure stability, flow accuracy, and repeatability.

 

Specifications :

Analytical System

Model P100
Liquid Infusion System Dual-piston reciprocating parallel pump, equipped with a binary high-pressure mixer
Flow Rate Range 0.001-10 mL/min
Max Output Pressure 42 MPa
Flow Accuracy <±1%
Flow Precision RSD<0.07%
Qualitative Repeatability RSD6 w 0.1% (naphthalene/methanol standards)
Quantitative Repeatability RSD6 < 0.3% (naphthalene/methanol standards)
Pressure Fluctuation 0.1 MPa
Power Supply 220V/110V

 

Semi-Preparation System

Model P100SP (40 mL semi-preparation system)
Flow Rate Range 0.01-40 mL/min
Pressure Range 0-25 MPa
Flow Accuracy ±2%
Flow Rate Accuracy RSD<0.1%

 

High Pressure Semi-Preparation & High Pressure Preparation Systems

Model P100HSP (50mL)
High Pressure Semi-Preparation System
P100HP (120mL)
High Pressure Preparation System
Flow Rate Range 0.01-50 mL/min 0.01-120 mL/min
Pressure Range 0-42 MPa 0-42 MPa
Flow Accuracy ±2% ±2%
Flow Rate Accuracy RSD RSD

Analytical System

Model P100
Liquid Infusion System Dual-piston reciprocating parallel pump, equipped with a binary high-pressure mixer
Flow Rate Range 0.001-10 mL/min
Max Output Pressure 42 MPa
Flow Accuracy <±1%
Flow Precision RSD<0.07%
Qualitative Repeatability RSD6 w 0.1% (naphthalene/methanol standards)
Quantitative Repeatability RSD6 < 0.3% (naphthalene/methanol standards)
Pressure Fluctuation 0.1 MPa
Power Supply 220V/110V

 

Semi-Preparation System

Model P100SP (40 mL semi-preparation system)
Flow Rate Range 0.01-40 mL/min
Pressure Range 0-25 MPa
Flow Accuracy ±2%
Flow Rate Accuracy RSD<0.1%

 

High Pressure Semi-Preparation & High Pressure Preparation Systems

Model P100HSP (50mL)
High Pressure Semi-Preparation System
P100HP (120mL)
High Pressure Preparation System
Flow Rate Range 0.01-50 mL/min 0.01-120 mL/min
Pressure Range 0-42 MPa 0-42 MPa
Flow Accuracy ±2% ±2%
Flow Rate Accuracy RSD RSD

Product Video:

Frequently Asked Questions

1What applications are supported by the AELAB P100HSP Series?
It supports analytical, semi-preparative, and preparative chromatography including purification, isolation, and fraction collection.
2What is the maximum pressure capacity of the system?
All high-pressure models operate up to 42 MPa.
3Can the system maintain precise low-flow operation?
Yes, the analytical pump (P100) delivers 0.001–10 mL/min with high precision and RSD<0.07%.
4Does the pump support solvent mixing?
Yes, the P100 analytical model includes a binary high-pressure mixer.
5What are the recommended power requirements?
The analytical model operates on 220V/110V as specified in the catalog.

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