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AELAB K2025 High Performance Liquid Chromatography System

The AELAB K2025 High Performance Liquid Chromatography system delivers precise analytical separation with stable pumping, accurate sampling, and a high-sensitivity detection platform. Designed for laboratory and industrial workflows, the K2025 ensures reliable quantitative results and streamlined operation through an intuitive chromatography workstation and FDA 21 CFR Part 11–compliant data management.
Modles : K2025
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The AELAB K2025 High Performance Liquid Chromatography system is engineered for precise and stable chromatographic separation across pharmaceutical, environmental, food, biochemical, and industrial quality control applications. Built with reliable components and an optimized flow control design, the K2025 ensures long-term operational stability and consistent analytical accuracy. Its chromatographic workstation provides streamlined method setup, real-time instrument monitoring, and secure data processing with FDA 21 CFR Part 11 compliance.

The K2025 integrates AELAB’s advanced pumping and sampling technology, offering high sensitivity, repeatability, and robust performance in routine and research-grade HPLC analysis. The platform is designed to meet modern laboratory requirements for traceability, workflow efficiency, and precision quantification.

 

⚙️ Design & Construction

The AELAB K2025 features a modular architecture with independent pump, sampler, and detector units positioned in a vertically stacked or bench-top configuration. Each module uses durable, high-quality materials to ensure mechanical stability and long-term reliability. Integrated solvent reservoirs, front-access service points, and an ergonomic layout support efficient routine maintenance. The instrument’s optical and hydraulic pathways are engineered to minimize baseline drift, enhance flow accuracy, and maintain chromatographic reproducibility under continuous use.

 

🔬 Working Principle / Testing Method

The K2025 performs liquid chromatographic separation by delivering a controlled mobile phase through a high-precision pump, introducing samples via an automated or manual injector, and detecting analytes using a high-sensitivity detection module. The workstation software processes chromatographic peaks, calculates retention times and area normalization, and supports quantitative and qualitative analysis. Real-time visualization, baseline tracking, and status monitoring ensure reliable operation throughout the analytical run.

 

💡 Key Advantages

  • Stabilizes mobile-phase flow with high-precision pumping technology
  • Supports reproducible sampling for routine quantitative analysis
  • Ensures secure workflow compliance through FDA 21 CFR Part 11 data management
  • Offers intuitive chromatographic workstation with clear functional, navigation, and monitoring zones
  • Provides long-term operational reliability through optimized mechanical design
  • Improves data traceability with integrated database mode and audit trails
  • Compatible with diverse laboratory HPLC workflows including pharmaceuticals, environmental testing, and food analysis

 

🔗 Connectivity & Integration

The K2025 chromatographic workstation supports direct PC integration, secure method storage, audit trails, and compliant data handling. USB, LAN, and software-controlled system modules enable synchronized instrument control, automated data acquisition, and compatibility with GLP and regulatory documentation workflows.

 

🧠 Model Insight

Model Specifications
K2025 High Performance Liquid Chromatography system with precision pump, sampling module, and chromatographic workstation. Full technical parameters required from catalog.

 

🧪 Testing Applications

The AELAB K2025 is suitable for analytical workflows in pharmaceuticals, environmental monitoring, food and beverage quality control, petrochemical analysis, biochemical research, and industrial formulation testing. It supports quantitative impurity profiling, method validation, stability studies, and routine chromatographic separations.

 

Compliance & Quality Assurance

The K2025 fully supports GLP-aligned workflows and complies with FDA 21 CFR Part 11 through secure data management, electronic signatures, audit trails, and controlled access. All system modules follow AELAB manufacturing standards and undergo rigorous reliability testing to ensure traceable, repeatable, and stable analytical performance.

 

Specifications :

Flow rate range 0.001mL/min~10.000mL/min
Pump type Isocratic(P1), Binary(P2), Quaternary(P4)
Maximum pressure 62MPa
Plunger rinsing Supported

 

K2025AS Autosampler

  • Precise injection volume: The K2025 autosampler adopts a patented integrated constant pressure needle and a precise syringe pump, which ensures accurate injection volume and excellent linearity, making the results more precise and accurate.

 

Specifications 

Sample capacity 108,2mL(96&384 well plates)
Injection range 0-100µL
Injection mode Low-loss, microliter carrying, full-loop
Injection time Minimum to 5s
Carryover 0.003%
Degassing unit Online degassing(optional)
Temperature control 4-40°C(optional)

 

K2025CO Column Oven

* Precise temperature control ensures good separation and repeatability

Using fuzzy PID intelligent temperature control algorithm, ban-based air circulation, and multiple insulation layer

design, the column temperature is more accurate, stable, and uniform, the temperature stability is±0.1℃, and the

temperature for each analysis are constant and consistent.

* Triple protection, more safe to use:Real-time liquid leak protection, intelligent monitoring of Peltier and cavity temperature, over-temperature power-off protection, triple safety protection designs, effectively prevents accidental liquid leakage and dangers caused by over-heating.

 

Specifications 

Operating principle Peltier element and fan-based forced air
Temperature range

5 oC above ambient to 85oC

10 oC below ambient to 85oC

 

K2025UVD UV-Vis Detector

Low LOD: The high-throughput optical path, reference subtraction algorithm, and ultra-precise signal acquisition circuit ensure

the detector’s excellent sensitivity. Sample:1.0×10-7g/mL Naphthalene. Column: C18, 4.6×250mm, 5μm. Mobile phase: 95:5=Methanol: Water. Flow rate: 1.0mL/min. Injection Volume: 20 μL. Wavelength: 254nm

Wide linearity: The UVD covers a wide linear range of 2.5AU, making it easier to analyze high concentration samples

 

Light source Deuterium(transmission type) and Tungsten lamp
Wavelength range 190-800nm
Wavelength accuracy +/- 1nm
Wavelength precision +/- 0.1nm
Linearity >2.5AU
Wavelength calibration

Mercury lamp

 

 

K2025DAD Diode Array  Detector

Light source Deuterium (transmission type) & Tungsten lamp
Wavelength range 190~800nm
Slit width 1nm, 2nm, 4nm, 8nm
Wavelength accuracy +/- 1nm
Wavelength precision +/-0.1nm
Linearity >2.0AU
Wavelength calibration Holmium glass
Flow rate range 0.001mL/min~10.000mL/min
Pump type Isocratic(P1), Binary(P2), Quaternary(P4)
Maximum pressure 62MPa
Plunger rinsing Supported

 

K2025AS Autosampler

  • Precise injection volume: The K2025 autosampler adopts a patented integrated constant pressure needle and a precise syringe pump, which ensures accurate injection volume and excellent linearity, making the results more precise and accurate.

 

Specifications 

Sample capacity 108,2mL(96&384 well plates)
Injection range 0-100µL
Injection mode Low-loss, microliter carrying, full-loop
Injection time Minimum to 5s
Carryover 0.003%
Degassing unit Online degassing(optional)
Temperature control 4-40°C(optional)

 

K2025CO Column Oven

* Precise temperature control ensures good separation and repeatability

Using fuzzy PID intelligent temperature control algorithm, ban-based air circulation, and multiple insulation layer

design, the column temperature is more accurate, stable, and uniform, the temperature stability is±0.1℃, and the

temperature for each analysis are constant and consistent.

* Triple protection, more safe to use:Real-time liquid leak protection, intelligent monitoring of Peltier and cavity temperature, over-temperature power-off protection, triple safety protection designs, effectively prevents accidental liquid leakage and dangers caused by over-heating.

 

Specifications 

Operating principle Peltier element and fan-based forced air
Temperature range

5 oC above ambient to 85oC

10 oC below ambient to 85oC

 

K2025UVD UV-Vis Detector

Low LOD: The high-throughput optical path, reference subtraction algorithm, and ultra-precise signal acquisition circuit ensure

the detector’s excellent sensitivity. Sample:1.0×10-7g/mL Naphthalene. Column: C18, 4.6×250mm, 5μm. Mobile phase: 95:5=Methanol: Water. Flow rate: 1.0mL/min. Injection Volume: 20 μL. Wavelength: 254nm

Wide linearity: The UVD covers a wide linear range of 2.5AU, making it easier to analyze high concentration samples

 

Light source Deuterium(transmission type) and Tungsten lamp
Wavelength range 190-800nm
Wavelength accuracy +/- 1nm
Wavelength precision +/- 0.1nm
Linearity >2.5AU
Wavelength calibration

Mercury lamp

 

 

K2025DAD Diode Array  Detector

Light source Deuterium (transmission type) & Tungsten lamp
Wavelength range 190~800nm
Slit width 1nm, 2nm, 4nm, 8nm
Wavelength accuracy +/- 1nm
Wavelength precision +/-0.1nm
Linearity >2.0AU
Wavelength calibration Holmium glass

Frequently Asked Questions

1What applications is the AELAB K2025 HPLC system designed for?
It supports pharmaceutical, environmental, biochemical, petrochemical, and food analysis workflows requiring precise chromatographic separation.
2Does the K2025 system comply with FDA 21 CFR Part 11?
Yes, the chromatographic workstation provides database mode, audit trails, and secure electronic records in compliance with FDA 21 CFR Part 11.
3What advantages does the K2025 offer in routine testing?
It provides stable flow control, precise sampling, high-sensitivity detection, and reliable long-term operation.
4Can the K2025 export chromatographic data?
Yes, data can be saved, exported, and archived through the integrated workstation software with traceable file structures.
5What specifications are required before installation?
Full technical details (pump pressure, flow rate, detector type, column oven range, power supply) must be confirmed from the official AELAB catalog.

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