This article examines the challenges and solutions for analyzing high-salt matrices in ICP-MS. It addresses issues such as spectral interferences, matrix effects, and reduced sensitivity, while introducing methods like ion-exchange resins, dilution, and filtration to improve accuracy and recovery rates. Advanced techniques like ICP-OES and ICP-MS, combined with these approaches, enhance the analysis of complex samples. This article is valuable for laboratories and researchers in various scientific and industrial fields.