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AELAB KH-3000Plus Thin Layer Chromatography Scanner for Quantitative TLC Analysis

The AELAB KH-3000Plus thin layer chromatography scanner performs high-precision quantitative and qualitative TLC analysis using photometric and imaging detection. Covering a 190–900 nm spectral range with fluorescence, reflectance, and transmittance modes, the KH-3000Plus integrates automated strip spotting, image-guided scanning, and GLP-compliant data processing for advanced laboratory and pharmaceutical analysis.
Modles : KH Series
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The AELAB KH-3000Plus thin layer chromatography scanner is an all-round TLC analytical system designed for high-precision quantitative and qualitative thin layer chromatography. By integrating photometric scanning and advanced imaging detection, the KH-3000Plus enables simultaneous acquisition of spectral and image data for enhanced analytical accuracy.

Equipped with automated fluorescence filter switching, continuous variable apertures, and image trajectory tracking, the AELAB KH-3000Plus ensures stable, reproducible TLC analysis compliant with GMP, GLP, and FDA 21 CFR Part 11 requirements.

 

⚙️ Design & Construction

The AELAB KH-3000Plus thin layer chromatography scanner adopts a modular optical design incorporating tungsten, deuterium, and mercury lamps with automatic switching. A holographic grating monochromator and high-stability photomultiplier tube are integrated into a rigid analytical frame, ensuring optical stability and long-term scanning reproducibility.

 

🔬 Working Principle / Testing Method

The KH-3000Plus performs thin layer chromatography analysis using reflectance absorption, transmittance absorption, and fluorescence detection. Image-guided linear scanning automatically tracks chromatographic trajectories, while dual detectors simultaneously collect densitometric and imaging data for accurate Rf determination and quantitative evaluation.

 

💡 Key Advantages

  • Simultaneous photometric and imaging detection for enhanced TLC accuracy
  • Fully automatic fluorescence filter wheel with up to 8 filter positions
  • 24-bit A/D signal conversion for high-precision data acquisition
  • Automated strip spotting integration for improved quantification repeatability
  • Image trajectory tracking for automatic scanning correction
  • Wide spectral coverage supporting UV, visible, and fluorescence TLC methods

 

🔗 Connectivity & Integration

The AELAB KH-3000Plus thin layer chromatography scanner connects via USB interface and operates under Windows 7 or Windows 10. It integrates seamlessly with automatic TLC developers, quantitative sprayers, immersion developers, and AELAB thin layer chromatography peripheral systems. Data export and electronic signature functions support compliant laboratory workflows.

 

🧪 Testing Applications

The AELAB KH-3000Plus thin layer chromatography scanner is widely used for pharmaceutical analysis, Chinese medicine fingerprint mapping, herbal medicine quality control, food safety testing, environmental monitoring, biochemical research, and material analysis requiring high-resolution TLC quantification.

 

Compliance & Quality Assurance

The AELAB KH-3000Plus is designed to support ISO-based laboratory workflows and complies with GMP, GLP, and FDA 21 CFR Part 11 requirements. Calibration stability, traceable data management, electronic signatures, and controlled user access ensure reliable quality assurance for regulated analytical laboratories.

 

Specifications :

Technical Specifications – AELAB KH-3000Plus Thin Layer Chromatography Scanner
Measurement Methods Reflectance Absorption, Transmittance Absorption, Fluorescence Method
Spectral Range (nm) 190–900 (Continuously Adjustable)
Light Source Tungsten Lamp, Deuterium Lamp, Mercury Lamp (Automatic Switching)
Monochromator Holographic Grating (1200 lines/mm)
Spectral Bandwidth (nm) 10 (Standard); Optional: 5, 10, 20
Wavelength Accuracy (nm) ±0.5
Wavelength Repeatability (nm) ≤0.1
Minimum Resolution 10–50 μm
Aperture Shift 254 nm, 365 nm, White Light (Fully Automatic)
Measurement Stage 200 mm × 200 mm Plates (300 mm × 200 mm Customizable)
Scanning Speed 0–120 mm/s
Analog-to-Digital Conversion 24-bit, 2 Channels, 20 μs, 2 Conversions
Chamber Illumination 254 nm, 365 nm × 8 W; White Light (Optional)
Filters K320, K360, K400, K450, K510, K550 (Standard); 8 Positions (Customizable)
Slit Size Length 0–8 mm, Width 0–4 mm (Continuously Adjustable, Computer-Controlled)
Detector Photomultiplier Tube
Data Acquisition 30000 DPS
Data Transmission 2000000 baud
Scanning Mode Linear Scanning
Operating System Windows 7 / Windows 10
Power Interface USB Interface, 220 V, 300 W
Technical Specifications – AELAB KH-3000Plus Thin Layer Chromatography Scanner
Measurement Methods Reflectance Absorption, Transmittance Absorption, Fluorescence Method
Spectral Range (nm) 190–900 (Continuously Adjustable)
Light Source Tungsten Lamp, Deuterium Lamp, Mercury Lamp (Automatic Switching)
Monochromator Holographic Grating (1200 lines/mm)
Spectral Bandwidth (nm) 10 (Standard); Optional: 5, 10, 20
Wavelength Accuracy (nm) ±0.5
Wavelength Repeatability (nm) ≤0.1
Minimum Resolution 10–50 μm
Aperture Shift 254 nm, 365 nm, White Light (Fully Automatic)
Measurement Stage 200 mm × 200 mm Plates (300 mm × 200 mm Customizable)
Scanning Speed 0–120 mm/s
Analog-to-Digital Conversion 24-bit, 2 Channels, 20 μs, 2 Conversions
Chamber Illumination 254 nm, 365 nm × 8 W; White Light (Optional)
Filters K320, K360, K400, K450, K510, K550 (Standard); 8 Positions (Customizable)
Slit Size Length 0–8 mm, Width 0–4 mm (Continuously Adjustable, Computer-Controlled)
Detector Photomultiplier Tube
Data Acquisition 30000 DPS
Data Transmission 2000000 baud
Scanning Mode Linear Scanning
Operating System Windows 7 / Windows 10
Power Interface USB Interface, 220 V, 300 W

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Frequently Asked Questions

1What types of TLC detection does the KH-3000Plus support?
It supports reflectance absorption, transmittance absorption, and fluorescence thin layer chromatography detection.
2Can the KH-3000Plus perform strip spotting automatically?
Yes, the KH-3000Plus supports semi-automatic strip spotting with high-precision stepper motor control.
3What spectral range does the instrument cover?
The scanner operates continuously from 190 nm to 900 nm.
4Is the system compliant with regulated laboratory standards?
Yes, it supports GMP, GLP, and FDA 21 CFR Part 11 electronic records and signatures.
5Can TLC image analysis be performed on the system?
Yes, the included imaging system enables image capture, Rf calculation, quantification, and report generation.

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